| ONLINE ONLY ARTICLES - CASE REPORT |
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| Year : 2022 | Volume
: 6
| Issue : 2 | Page : 150 |
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Toxic epidermal necrolysis due to dual infection of Mycoplasma pneumoniae and Streptococcus complicated by herpes simplex virus
Suma D Gudi, Sambasiviah Chidambara Murthy, Niveditha Nagaraja, Vandana Devendra
Department of Dermatology, Venereology, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, India
Correspondence Address:
Sambasiviah Chidambara Murthy
Department of Dermatology, Venereology, Vijayanagar Institute of Medical Sciences, Ballari - 583 104, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/cdr.cdr_135_20
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Stevens–Johnson syndrome and toxic epidermal necrolysis (TEN) are severe mucocutaneous reactions, characterized by blistering and epidermal sloughing. They are mainly caused by drugs and less commonly due to infections. A 9-year-old boy presented with fever, cough, atypical target lesions involving >30% of body surface area along with few erosions and positive pseudo-Nikolsky sign. Multiple mucous membranes were involved. Clinical features were consistent with TEN. Radiological and laboratory investigations showed evidence of Mycoplasma pneumonia and Group A Streptococcal infection. The course was further complicated by herpes simplex 1 infection. He responded well to systemic antibiotics, corticosteroids, cyclosporine, acyclovir, and supportive care. This report highlights the occurrence of TEN due to dual infections that further got complicated by a third infection.
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